diff --git a/docs/README.instructions.md b/docs/README.instructions.md
index b9eb2941a..dab198e1d 100644
--- a/docs/README.instructions.md
+++ b/docs/README.instructions.md
@@ -31,6 +31,7 @@ See [CONTRIBUTING.md](../CONTRIBUTING.md#adding-instructions) for guidelines on
| [ASP.NET REST API Development](../instructions/aspnet-rest-apis.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Faspnet-rest-apis.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode-insiders%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Faspnet-rest-apis.instructions.md) | Guidelines for building REST APIs with ASP.NET |
| [Astro Development Instructions](../instructions/astro.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Fastro.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode-insiders%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Fastro.instructions.md) | Astro development standards and best practices for content-driven websites |
| [AWS AppSync Event API Instructions](../instructions/aws-appsync.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Faws-appsync.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode-insiders%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Faws-appsync.instructions.md) | Production-grade guidance for AWS AppSync Event API handlers using APPSYNC_JS runtime restrictions, utilities, modules, and datasource patterns |
+| [AWS CDK Python Setup Instructions](../instructions/aws-cdk-python-setup.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Faws-cdk-python-setup.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode-insiders%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Faws-cdk-python-setup.instructions.md) | Setup instructions for AWS CDK Python projects |
| [Azure DevOps Pipeline YAML Best Practices](../instructions/azure-devops-pipelines.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Fazure-devops-pipelines.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode-insiders%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Fazure-devops-pipelines.instructions.md) | Best practices for Azure DevOps Pipeline YAML files |
| [Azure Functions Typescript](../instructions/azure-functions-typescript.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Fazure-functions-typescript.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode-insiders%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Fazure-functions-typescript.instructions.md) | TypeScript patterns for Azure Functions |
| [Azure Logic Apps and Power Automate Instructions](../instructions/azure-logic-apps-power-automate.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Fazure-logic-apps-power-automate.instructions.md)
[](https://aka.ms/awesome-copilot/install/instructions?url=vscode-insiders%3Achat-instructions%2Finstall%3Furl%3Dhttps%3A%2F%2Fraw.githubusercontent.com%2Fgithub%2Fawesome-copilot%2Fmain%2Finstructions%2Fazure-logic-apps-power-automate.instructions.md) | Guidelines for developing Azure Logic Apps and Power Automate workflows with best practices for Workflow Definition Language (WDL), integration patterns, and enterprise automation |
diff --git a/instructions/aws-cdk-python-setup.instructions.md b/instructions/aws-cdk-python-setup.instructions.md
new file mode 100644
index 000000000..fa4b9868d
--- /dev/null
+++ b/instructions/aws-cdk-python-setup.instructions.md
@@ -0,0 +1,137 @@
+---
+description: 'Setup instructions for AWS CDK Python projects'
+applyTo: '**/*.py'
+---
+
+# AWS CDK Python Setup Instructions
+
+This instructions file provides guidance for setting up and working with AWS CDK (Cloud Development Kit) projects using Python. These instructions apply to Python files in CDK projects.
+
+## Prerequisites
+
+Before starting with AWS CDK Python development, ensure you have the following installed:
+
+- **Node.js** (version 14.15.0 or later) - Required for the AWS CDK CLI
+- **Python** (version 3.7 or later)
+- **AWS CLI** - For configuring AWS credentials and managing AWS resources
+- **Git** - For version control
+
+## Installation Steps
+
+### 1. Install AWS CDK CLI
+
+The AWS CDK CLI is a Node.js package that provides the `cdk` command.
+
+```bash
+npm install -g aws-cdk
+```
+
+Verify the installation:
+
+```bash
+cdk --version
+```
+
+### 2. Configure AWS Credentials
+
+Install and configure the AWS CLI:
+
+```bash
+# Install AWS CLI (if not already installed)
+# On macOS, you can use Homebrew:
+brew install awscli
+
+# Configure AWS credentials
+aws configure
+```
+
+Enter your AWS Access Key ID, Secret Access Key, default region, and output format when prompted.
+
+### 3. Create a New CDK Project
+
+Create a new directory for your CDK project and initialize it:
+
+```bash
+mkdir my-cdk-project
+cd my-cdk-project
+cdk init app --language python
+```
+
+This creates a basic CDK app structure with:
+- `app.py` - Main application entry point
+- `my_cdk_project/` - Python package containing your CDK stacks
+- `requirements.txt` - Python dependencies
+- `cdk.json` - CDK configuration
+
+### 4. Set Up Python Virtual Environment
+
+CDK Python projects include a virtual environment. Activate it:
+
+```bash
+# On macOS/Linux
+source .venv/bin/activate
+
+# On Windows
+.venv\Scripts\activate
+```
+
+### 5. Install Python Dependencies
+
+Install the required Python packages:
+
+```bash
+pip install -r requirements.txt
+```
+
+The main dependencies include:
+- `aws-cdk-lib` - Core CDK constructs
+- `constructs` - Base construct library
+
+## Development Workflow
+
+### Synthesize CloudFormation Templates
+
+Generate CloudFormation templates from your CDK code:
+
+```bash
+cdk synth
+```
+
+This creates `cdk.out/` directory with synthesized templates.
+
+### Deploy to AWS
+
+Deploy your CDK stacks to AWS:
+
+```bash
+cdk deploy
+```
+
+Review the changes and confirm deployment when prompted.
+
+### Bootstrap (First Time Only)
+
+If deploying to a new AWS account/region, bootstrap the environment:
+
+```bash
+cdk bootstrap
+```
+
+This sets up necessary resources like S3 buckets for storing assets.
+
+## Best Practices
+
+- Always activate the virtual environment before working
+- Use `cdk diff` to preview changes before deployment
+- Test deployments in development accounts first
+- Use AWS CDK constructs for infrastructure as code
+- Follow Python naming conventions and structure
+
+## Troubleshooting
+
+- Ensure AWS credentials are properly configured
+- Check that the correct AWS region is set
+- Verify Node.js and Python versions meet requirements
+- Use `cdk doctor` to diagnose common issues
+
+For detailed documentation, refer to the official AWS CDK documentation and the attached `awscdk.pdf` file.