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2 changes: 2 additions & 0 deletions .gitignore
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resources/
public/
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title = "Corticothalamic circuit mechanisms underlying brain region and ageing variations in resting-state alpha activity"
date = 2025-01-01T00:00:00
draft = false

# Authors. Comma separated list, e.g. `["Bob Smith", "David Jones"]`.
authors = ["Sorenza P. Bastiaens", "Davide Momi", "L Rokos", "Taha Morshedzadeh", "Kevin Kadak", "Mohammad P. Oveisi", "John D. Griffiths"]

# Publication type.
# Legend:
# 0 = Uncategorized
# 1 = Conference paper
# 2 = Journal article
# 3 = Manuscript
# 4 = Report
# 5 = Book
# 6 = Book section
publication_types = ["2"]

# Publication name and optional abbreviated version.
publication = "Imaging Neuroscience"
publication_short = "Imaging Neurosci."

# Abstract and optional shortened version.
abstract = ""

abstract_short = ""

# Is this a selected publication? (true/false)
selected = true

# Projects (optional).
# Associate this publication with one or more of your projects.
# Simply enter your project''s folder or file name without extension.
# E.g. `projects = ["deep-learning"]` references
# `content/project/deep-learning/index.md`.
# Otherwise, set `projects = []`.
projects = ["EEG", "alpha rhythms"]

# Tags (optional).
# Set `tags = []` for no tags, or use the form `tags = ["A Tag", "Another Tag"]` for one or more tags.
tags = ["EEG", "alpha rhythms", "corticothalamic"]

# Links (optional).
#url_pdf = ""
url_code = "https://github.com/GriffithsLab/Bastiaens2025_CorticothalamicRestingParametrization"

# Custom links (optional).
# Uncomment line below to enable. For multiple links, use the form `[{...}, {...}, {...}]`.
#url_custom = [{name = "url", url = ""}]

# Digital Object Identifier (DOI)
#doi = ""

# Does this page contain LaTeX math? (true/false)
math = true

# Featured image
# To use, add an image named `featured.jpg/png` to your page`s folder.
[image]
# # Caption (optional)
# #caption = "Image credit: [**Unsplash**](https://unsplash.com/photos/pLCdAaMFLTE)"
# Focal point (optional)
# # Options: Smart, Center, TopLeft, Top, TopRight, Left, Right, BottomLeft, Bottom, BottomRight
focal_point = "BottomLeft"
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title = "Towards a mathematical theory of rTMS-induced neural plasticity"
date = 2025-07-01T00:00:00
draft = false

# Authors. Comma separated list, e.g. `["Bob Smith", "David Jones"]`.
authors = ["John D. Griffiths", "Kevin Kadak"]

# Publication type.
# Legend:
# 0 = Uncategorized
# 1 = Conference paper
# 2 = Journal article
# 3 = Manuscript
# 4 = Report
# 5 = Book
# 6 = Book section
publication_types = ["2"]

# Publication name and optional abbreviated version.
publication = "Clinical Neurophysiology"
publication_short = "Clin. Neurophysiol."

# Abstract and optional shortened version.
abstract = ""

abstract_short = ""

# Is this a selected publication? (true/false)
selected = true

# Projects (optional).
# Associate this publication with one or more of your projects.
# Simply enter your project''s folder or file name without extension.
# E.g. `projects = ["deep-learning"]` references
# `content/project/deep-learning/index.md`.
# Otherwise, set `projects = []`.
projects = ["brain_stimulation", "EEG"]

# Tags (optional).
# Set `tags = []` for no tags, or use the form `tags = ["A Tag", "Another Tag"]` for one or more tags.
tags = ["brain stimulation", "rTMS", "neural plasticity", "computational modelling"]

# Links (optional).
url_code = "https://github.com/GriffithsLab/Kadak2025_alpha-subharmonics-rtms-eeg"

# Custom links (optional).
# Uncomment line below to enable. For multiple links, use the form `[{...}, {...}, {...}]`.
url_custom = [{name = "url", url = "https://www.sciencedirect.com/science/article/abs/pii/S1388245725006789"}]

# Digital Object Identifier (DOI)
doi = "10.1016/j.clinph.2025.2110826"

# Does this page contain LaTeX math? (true/false)
math = true

# Featured image
# To use, add an image named `featured.jpg/png` to your page`s folder.
[image]
# # Caption (optional)
# #caption = "Image credit: [**Unsplash**](https://unsplash.com/photos/pLCdAaMFLTE)"
# Focal point (optional)
# # Options: Smart, Center, TopLeft, Top, TopRight, Left, Right, BottomLeft, Bottom, BottomRight
focal_point = "BottomLeft"
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title = "Alpha rhythm subharmonics underlie responsiveness to theta burst stimulation via calcium metaplasticity"
date = 2025-11-24T00:00:00
draft = false

# Authors. Comma separated list, e.g. `["Bob Smith", "David Jones"]`.
authors = ["Kevin Kadak", "Davide Momi", "Zheng Wang", "Sorenza P. Bastiaens", "Mohammad P. Oveisi", "Taha Morshedzadeh", "Minarose Ismail", "Jan Fousek", "John D. Griffiths"]

# Publication type.
# Legend:
# 0 = Uncategorized
# 1 = Conference paper
# 2 = Journal article
# 3 = Manuscript
# 4 = Report
# 5 = Book
# 6 = Book section
publication_types = ["2"]

# Publication name and optional abbreviated version.
publication = "eLife"
publication_short = "eLife"

# Abstract and optional shortened version.
abstract = "Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive technique to modulate brain activity, often used in treating Major Depressive Disorder (MDD) by targeting fronto-limbic circuitry. Despite its clinical utility, optimizing rTMS protocols remains challenging due to the complex and variable effects of stimulation parameter changes on synaptic plasticity. Oscillatory brain activity, measurable via Electroencephalography (EEG), serves as a biomarker for functional circuits and treatment response. To better understand the impact of rTMS on brain oscillations and connectivity, we used computational modeling of corticothalamic circuits to explore the mechanisms of stimulus-induced plasticity. We integrated calcium-dependent plasticity (CaDP) with Bienenstock-Cooper-Munro (BCM) metaplasticity formulations in a neural population model of resting-state EEG. By varying protocol parameters, we simulated iTBS effects on spectral power, synaptic efficacy, and calcium concentrations. Our findings highlight a resonance between theta stimulation and individual resting-state alpha rhythms, enhancing incoming excitatory long-term depression (LTD) and inhibitory long-term potentiation (LTP), leading to corticothalamic feed-forward inhibition (FFI). Induced effects were encapsulated by a weakening of corticothalamic loops and enhancement of intrathalamic loops. This work offers a novel paradigm for individualizing iTBS treatments, provides insights into the neurophysiological basis of clinical responsiveness, and offers a framework with which to derive tailored protocols."

abstract_short = ""

# Is this a selected publication? (true/false)
selected = true

# Projects (optional).
# Associate this publication with one or more of your projects.
# Simply enter your project''s folder or file name without extension.
# E.g. `projects = ["deep-learning"]` references
# `content/project/deep-learning/index.md`.
# Otherwise, set `projects = []`.
projects = ["brain_stimulation", "EEG"]

# Tags (optional).
# Set `tags = []` for no tags, or use the form `tags = ["A Tag", "Another Tag"]` for one or more tags.
tags = ["brain stimulation", "EEG", "rTMS", "TBS", "computational modelling"]

# Links (optional).
url_pdf = "https://elifesciences.org/download/aHR0cHM6Ly9jZG4uZWxpZmVzY2llbmNlcy5vcmcvYXJ0aWNsZXMvMTA4NTYzL2VsaWZlLTEwODU2My12MS5wZGY/elife-108563-v1.pdf"
url_preprint = "https://doi.org/10.1101/2025.06.17.660153"
url_code = "https://github.com/GriffithsLab/Kadak2025_alpha-subharmonics-rtms-eeg"

# Custom links (optional).
# Uncomment line below to enable. For multiple links, use the form `[{...}, {...}, {...}]`.
url_custom = [{name = "url", url = "https://elifesciences.org/articles/108563"}]

# Digital Object Identifier (DOI)
doi = "10.7554/eLife.108563"

# Does this page contain LaTeX math? (true/false)
math = true

# Featured image
# To use, add an image named `featured.jpg/png` to your page`s folder.
[image]
# # Caption (optional)
# #caption = "Image credit: [**Unsplash**](https://unsplash.com/photos/pLCdAaMFLTE)"
# Focal point (optional)
# # Options: Smart, Center, TopLeft, Top, TopRight, Left, Right, BottomLeft, Bottom, BottomRight
focal_point = "BottomLeft"
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