⚠️ This Repository is Archived

This repository is now archived and is no longer maintained.

Why?

This project was part of the first generation of the Just DNA-Seq platform, which utilized the OakVar framework. We have since transitioned to a significantly more powerful and modern architecture.

What should I use instead?

We now use just-dna-lite, a lightweight yet more capable platform that brings several major improvements:

👉 Get started with just-dna-lite

Key Improvements in the New Generation:

• Enhanced Performance: Powered by a high-performance PRS engine (using DuckDB/Polars) that is up to 12x faster than traditional tools.
• AI Module Creator: A new agentic pipeline that allows you to turn research papers or PDFs into functional genetic annotation modules in minutes.
• Expanded Capabilities: Native support for over 5,000+ Polygenic Risk Scores from the PGS Catalog, epigenetic clocks, and comprehensive variant cross-referencing.
• Local & Private: Runs entirely on your machine via Podman/Docker—your genomic data never leaves your computer.
• Modern UI: Replaces older command-line workflows with an intuitive web interface for uploading VCF files and generating reports.

Most modules from the previous OakVar-based generation that remained scientifically relevant have been ported and optimized for this new platform. We recommend all users migrate to just-dna-lite for the latest features and updates.

just_prs

Polygenic risk score (PRS) postagregator for longevity report in OakVar. It is a part of Oakvar-Longevity module.

Installation

Installation through Oakvar

From Oakvar store:

ov module install just_prs

Or make git clone of the current repository directly into "postaggregators" folder of Oakvar:

git clone https://github.com/dna-seq/just_prs

Manual installation

Create a folder with the name "just_prs" in "postaggregators" folder of Oakvar and put it inside all the files from this git repository.

You can join our discord if you want to discuss the project or if you encountered any issues.