phylogenetic analyses informed by deep mutational scanning data

Protein Analysis and Classifier Toolkit

A tool for multiscale forward-time simulation of protein evolution.

Predicting mutation effects based on deep mutational scanning data

nf-core/deepmutscan is a reproducible, scalable, and community-curated pipeline for analyzing deep mutational scanning (DMS) data using shotgun DNA sequencing.

dseq: Deep sequencing analysis in dataframes (https://deepwiki.com/rraadd88/dseq)

nf-core/deepmutscan: a reproducible, scalable, and community-curated pipeline for analyzing deep mutational scanning (DMS) data using shotgun DNA sequencing

Preliminary analysis of a combined DMS dataset, including clustering and VEP benchmark

Deep mutational scan of human adenosine deaminase

Toward a formal cartography of protein function

Zero-shot protein language model pipeline for mutational tolerance scoring of antibiotic resistance genes in ESKAPE pathogens

Evaluating ESM-2 protein embeddings for variant effect prediction against Deep Mutational Scanning fitness scores